Notch Inhibition Promotes Differentiation of Liver Progenitor Cells into Hepatocytes via sox9b Repression in Zebrafish

• 主要な著者: Jacquelyn O. Russell (著者), Sungjin Ko (著者), Satdarshan P. Monga (著者), Donghun Shin (著者)
• フォーマット: 図書
• 出版事項: Hindawi Limited, 2019-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Liver regeneration after most forms of injury is mediated through the proliferation of hepatocytes. However, when hepatocyte proliferation is impaired, such as during chronic liver disease, liver progenitor cells (LPCs) arising from the biliary epithelial cell (BEC) compartment can give rise to hepa...