Identification of Novel Loci Involved in Adalimumab Response in Crohn's Disease Patients Using Integration of Genome Profiling and Isoform-Level Immune-Cell Deconvoluted Transcriptome Profiling of Colon Tissue

Crohn's disease is a consequence of dysregulated inflammatory response to the host's microbiota. Although anti-TNF treatment improves the quality of the patient's life, a large proportion of patients lose response to the treatment. The past decade of research has led to a continuum of...

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Päätekijät: Mario Gorenjak (Tekijä), Gregor Jezernik (Tekijä), Martina Krušič (Tekijä), Pavel Skok (Tekijä), Uroš Potočnik (Tekijä)
Aineistotyyppi: Kirja
Julkaistu: MDPI AG, 2022-09-01T00:00:00Z.
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