CYP2S1 and CYP2W1 expression is associated with patient survival in breast cancer

• Main Authors: Radhika Aiyappa‐Maudsley (Author), Sarah J Storr (Author), Emad A Rakha (Author), Andrew R Green (Author), Ian O Ellis (Author), Stewart G Martin (Author)
• Format: Book
• Published: Wiley, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The cytochrome P450 family of enzymes metabolise a wide range of compounds and play important roles in breast cancer pathogenesis due to their involvement in estrogen metabolism and the production of carcinogenic metabolites during this process. The orphan CYPs, CYP2S1, and CYP2W1 are repor...