Design, synthesis, antitumor evaluation, and molecular docking of novel pyrrolo[2,3-d]pyrimidine as multi-kinase inhibitors

• Main Authors: Ashwag S. Alanazi (Author), Tebyan O. Mirgany (Author), Nawaf A. Alsaif (Author), Aisha A. Alsfouk (Author), Mohammed M. Alanazi (Author)
• פורמט: ספר
• יצא לאור: Elsevier, 2023-06-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

In the last twenty years, protein kinases have been identified as important targets for cancer therapy. In order to prevent unexpected toxicity, medicinal chemists have always focused on discovering selective protein kinase inhibitors. However, cancer is a multifactorial process and its formation an...