An interaction between <it>Nrf2 </it>polymorphisms and smoking status affects annual decline in FEV₁: a longitudinal retrospective cohort study

• Main Authors: Hirota Tomomitsu (Author), Noguchi Emiko (Author), Iijima Hiroaki (Author), Naito Takashi (Author), Kaneko Yoshiko (Author), Sakamoto Tohru (Author), Masuko Hironori (Author), Tamari Mayumi (Author), Hizawa Nobuyuki (Author)
• Format: Book
• Published: BMC, 2011-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>An Nrf2-dependent response is a central protective mechanism against oxidative stress. We propose that particular genetic variants of the <it>Nrf2 </it>gene may be associated with a rapid forced expiratory volume in one s...