Metabolomics analysis elucidates unique influences on purine / pyrimidine metabolism by xanthine oxidoreductase inhibitors in a rat model of renal ischemia-reperfusion injury

Abstract Background Clinically applied as anti-gout drugs, xanthine oxidoreductase (XOR) inhibitors, especially the potent, selective, non-purine-analog XOR inhibitors febuxostat and topiroxostat, exert organ-protective effects. We tested the hypothesis that preservation of tissue concentrations of...

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Main Authors: Takashi Tani (Author), Ken Okamoto (Author), Megumi Fujiwara (Author), Akira Katayama (Author), Shuichi Tsuruoka (Author)
Format: Book
Published: BMC, 2019-08-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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