CXCL2-mediated ATR/CHK1 signaling pathway and platinum resistance in epithelial ovarian cancer

• Main Authors: Sipei Nie (Author), Yicong Wan (Author), Hui Wang (Author), Jinhui Liu (Author), Jing Yang (Author), Rui Sun (Author), Huangyang Meng (Author), Xiaolin Ma (Author), Yi Jiang (Author), Wenjun Cheng (Author)
• Format: Book
• Published: BMC, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Tumor microenvironment and chemokines play a significant role in cancer chemoresistance. This study was designed to reveal the important role of CXCL2 in platinum resistance in epithelial ovarian cancer (EOC). Differently expressed (DE) genes were screen out based on analysis of GSE114206 d...