Association of common variants in JAK2 gene with reduced risk of metabolic syndrome and related disorders

• Main Authors: Penas-Steinhardt Alberto (Author), Tellechea¹ Mariana L (Author), Gomez-Rosso Leonardo (Author), Brites Fernando (Author), Frechtel Gustavo D (Author), Poskus Edgardo (Author)
• Format: Book
• Published: BMC, 2011-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Disturbances in leptin and insulin signaling pathways are related to obesity and metabolic syndrome (MS) with increased risk of diabetes and cardiovascular disease. Janus kinase 2 (JAK2) is a tyrosine kinase involved in the activatio...