Renal interstitial fibrosis is reduced in high-fat diet-induced obese pigs following renal denervation from the intima and adventitia of the renal artery

• Main Authors: Binbin Zhu (Author), Yahui Liu (Author), Datun Qi (Author), Linwei Zhao (Author), Xiaohang Yang (Author), Enyong Su (Author), Zhongyu Zhu (Author), You Zhang (Author), Chuanyu Gao (Author)
• Format: Book
• Published: Karger Publishers, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background This study aims to compare whether two different routes of Renal denervation (RDN) from the intima and adventitia of the renal artery can reduce renal fibrosis in a pig model of hypertension induced by a high-fat diet and to explore possible molecular mechanisms. Methods Twenty-f...