Cyclo-(Phe-Tyr) as a novel cyclic dipeptide compound alleviates ischemic/reperfusion brain injury via JUNB/JNK/NF-κB and SOX5/PI3K/AKT pathways

• Main Authors: Jiale Cai (Author), Jiayin Liang (Author), Yutong Zhang (Author), Lin Shen (Author), Huiting Lin (Author), Tao Hu (Author), Sikai Zhan (Author), Meixia Xie (Author), Shengwang Liang (Author), Minghua Xian (Author), Shumei Wang (Author)
• Format: Book
• Published: Elsevier, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ischemic/reperfusion (IR) can cause adverse reactions including apoptosis, oxidative stress, and inflammation, but the existing therapeutic strategies have been limited. Moreover, the regulation of microglia plays an important role in brain injury after reperfusion. Hence, it is imperative to find n...