Synthesis and biological evaluation of some 4-aminoquinoline derivatives as potential antitubercular agents

• Main Authors: Shankar Alegaon (Author), Kamlesh Kashniyal (Author), Sanket Kuncolienkar (Author), Rohini Kavalapure (Author), Preeti Salve (Author), Mahesh Palled (Author), Shailendra Suryawanshi (Author), Sunil Jalalpure (Author)
• Format: Book
• Published: SpringerOpen, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Based on bioisosteric similarities with thiacetazone, a series of 7-chloro-4-aminoquinoline derivatives have been designed and synthesized. The target compounds were elucidated by NMR, mass, and FTIR spectral data. All synthesized compounds were evaluated for their in vitro antit...