LPM3770277, a Potent Novel CDK4/6 Degrader, Exerts Antitumor Effect Against Triple-Negative Breast Cancer

• Asıl Yazarlar: Jiahao Qiu (Yazar), Xinfa Bai (Yazar), Wenjing Zhang (Yazar), Mingxu Ma (Yazar), Wenyan Wang (Yazar), Ye Liang (Yazar), Hongbo Wang (Yazar), Jingwei Tian (Yazar), Pengfei Yu (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2022-04-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Triple negative breast cancer (TNBC) is a subtype of breast cancer with significant malignancy and poor prognosis but effective treatments are limited. Given the critical role of CDK4/6 in cell cycle and the apparent success of CDK4/6 inhibitors against certain cancer, this study attempted to utiliz...