Development of a Gene and Nucleic Acid Delivery System for Skeletal Muscle Administration via Limb Perfusion Using Nanobubbles and Ultrasound

• Главные авторы: Shohko Sekine (Автор), Sayaka Mayama (Автор), Nobuaki Nishijima (Автор), Takuo Kojima (Автор), Yoko Endo-Takahashi (Автор), Yuko Ishii (Автор), Hitomi Shiono (Автор), Saki Akiyama (Автор), Akane Sakurai (Автор), Sanae Sashida (Автор), Nobuhito Hamano (Автор), Rui Tada (Автор), Ryo Suzuki (Автор), Kazuo Maruyama (Автор), Yoichi Negishi (Автор)
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• Опубликовано: MDPI AG, 2023-06-01T00:00:00Z.
• Предметы: article
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Strategies for gene and nucleic acid delivery to skeletal muscles have been extensively explored to treat Duchenne muscular dystrophy (DMD) and other neuromuscular diseases. Of these, effective intravascular delivery of naked plasmid DNA (pDNA) and nucleic acids into muscles is an attractive approac...