Construction of miRNA-mRNA regulatory network indicates potential biomarkers for primary open-angle glaucoma

• Main Authors: Xiaoyu Zhou (Author), Feng Zhang (Author), Xinyue Zhang (Author), Dengming Zhou (Author), Yang Zhao (Author), Baihua Chen (Author), Xuanchu Duan (Author)
• Format: Book
• Published: BMC, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Trabecular meshwork (TM) dysfunction-induced elevation of intraocular pressure has been identified as the main risk factor of irreversible optic nerve injury in Primary open‑angle glaucoma (POAG). Increasing evidences suggest that microRNA (miRNA) plays a vital role in the pathog...