STAT5 is required for lipid breakdown and beta-adrenergic responsiveness of brown adipose tissue

• Main Authors: Doris Kaltenecker (Author), Katrin Spirk (Author), Frank Ruge (Author), Florian Grebien (Author), Marco Herling (Author), Anne Rupprecht (Author), Lukas Kenner (Author), Elena E. Pohl (Author), Kristina M. Mueller (Author), Richard Moriggl (Author)
• Format: Book
• Published: Elsevier, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Increasing energy expenditure through activation of brown adipose tissue (BAT) thermogenesis is an attractive approach to counteract obesity. It is therefore essential to understand the molecular mechanisms that control BAT functions. Until now several members of the Janus kinase (JAK) -...