Junín virus infection activates the type I interferon pathway in a RIG-I-dependent manner.

• Päätekijät: Cheng Huang (Tekijä), Olga A Kolokoltsova (Tekijä), Nadezdha E Yun (Tekijä), Alexey V Seregin (Tekijä), Allison L Poussard (Tekijä), Aida G Walker (Tekijä), Allan R Brasier (Tekijä), Yingxin Zhao (Tekijä), Bing Tian (Tekijä), Juan Carlos de la Torre (Tekijä), Slobodan Paessler (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Junín virus (JUNV), an arenavirus, is the causative agent of Argentine hemorrhagic fever, an infectious human disease with 15-30% case fatality. The pathogenesis of AHF is still not well understood. Elevated levels of interferon and cytokines are reported in AHF patients, which might be correlated...