Design and Microwave Synthesis of New (5<i>Z</i>) 5-Arylidene-2-thioxo-1,3-thiazolinidin-4-one and (5<i>Z</i>) 2-Amino-5-arylidene-1,3-thiazol-4(5<i>H</i>)-one as New Inhibitors of Protein Kinase DYRK1A

• Main Authors: Khadidja Bourahla (Author), Solène Guihéneuf (Author), Emmanuelle Limanton (Author), Ludovic Paquin (Author), Rémy Le Guével (Author), Thierry Charlier (Author), Mustapha Rahmouni (Author), Emilie Durieu (Author), Olivier Lozach (Author), François Carreaux (Author), Laurent Meijer (Author), Jean-Pierre Bazureau (Author)
• Format: Book
• Published: MDPI AG, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Here, we report on the synthesis of libraries of new 5-arylidene-2-thioxo-1,3-thiazolidin-4-ones 3 (twenty-two compounds) and new 2-amino-5-arylidene-1,3-thiazol-4(5<i>H</i>)-ones 5 (twenty-four compounds) with stereo controlled <i>Z</i>-geometry under microwave irradiation....