Topical treatment with gallium maltolate reduces Treponema pallidum subsp. pertenue burden in primary experimental lesions in a rabbit model of yaws.
<h4>Background</h4>Gallium is a semi-metallic element known since the 1930s to have antimicrobial activity. This activity stems primarily from gallium's ability to mimic trivalent iron and disrupt specific Fe(III)-dependent pathways, particularly DNA synthesis (due to inhibition of...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Book |
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Public Library of Science (PLoS),
2019-01-01T00:00:00Z.
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