Mek1Y130C mice recapitulate aspects of human cardio-facio-cutaneous syndrome

• Главные авторы: Rifdat Aoidi (Автор), Nicolas Houde (Автор), Kim Landry-Truchon (Автор), Michael Holter (Автор), Kevin Jacquet (Автор), Louis Charron (Автор), Suguna Rani Krishnaswami (Автор), Benjamin D. Yu (Автор), Katherine A. Rauen (Автор), Nicolas Bisson (Автор), Jason Newbern (Автор), Jean Charron (Автор)
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• Опубликовано: The Company of Biologists, 2018-03-01T00:00:00Z.
• Предметы: article
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The RAS/MAPK signaling pathway is one of the most investigated pathways, owing to its established role in numerous cellular processes and implication in cancer. Germline mutations in genes encoding members of the RAS/MAPK pathway also cause severe developmental syndromes collectively known as RASopa...