Mek1Y130C mice recapitulate aspects of human cardio-facio-cutaneous syndrome

Mek1Y130C mice recapitulate aspects of human cardio-facio-cutaneous syndrome

The RAS/MAPK signaling pathway is one of the most investigated pathways, owing to its established role in numerous cellular processes and implication in cancer. Germline mutations in genes encoding members of the RAS/MAPK pathway also cause severe developmental syndromes collectively known as RASopa...

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Main Authors: Rifdat Aoidi (Author), Nicolas Houde (Author), Kim Landry-Truchon (Author), Michael Holter (Author), Kevin Jacquet (Author), Louis Charron (Author), Suguna Rani Krishnaswami (Author), Benjamin D. Yu (Author), Katherine A. Rauen (Author), Nicolas Bisson (Author), Jason Newbern (Author), Jean Charron (Author)
Format: Book
Published: The Company of Biologists, 2018-03-01T00:00:00Z.
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