Reconstructed Human Epidermis: An Alternative Approach for In Vitro Bioequivalence Testing of Topical Products

• Main Authors: Ana Sofia Agonia (Author), Ana Palmeira- (Author), Catarina Cardoso (Author), Cátia Augusto (Author), Christian Pellevoisin (Author), Christelle Videau (Author), Ricardo Jorge Dinis-Oliveira (Author), Rita Palmeira- (Author)
• Format: Book
• Published: MDPI AG, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The use of in vitro human skin permeation tests is of value when addressing the quality and equivalence of topical drug products in Europe and the US. Human skin is the membrane of choice for these studies. The use of human skin as a membrane is hindered by limited access, high variability of result...