Formulation and Physicochemical Characterization of Buccoadhesive Microspheres Containing Diclofenac Sodium

• Autori principali: Mitra Jelvehgari (Autore), Hadi Valizadeh (Autore), Ramin Jalali Motlagh (Autore), Hassan Montazam (Autore)
• Natura: Libro
• Pubblicazione: Tabriz University of Medical Sciences, 2014-05-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Purpose: The present study involves preparation and evaluation of diclofenac buccal-mucoadhesive microparticles for prolongation of buccal residence time. Methods: The microparticles were prepared by modified double-emulsion dehydration method (O1/W/O2) using sodium carboxymethylcellulose (CMC-Na) a...