Identification of Smad-dependent and -independent signaling with transforming growth factor-β type 1/2 receptor inhibition in palatogenesis

• Main Authors: Yoshimi Suzuki (Author), Akira Nakajima (Author), Takayuki Kawato (Author), Koichi Iwata (Author), Mitsuru Motoyoshi (Author), Charles F. Shuler (Author)
• Format: Book
• Published: Elsevier, 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

TGF-β signaling is one of important function during palatal fusion. Three types of TGF-β receptor (TβR1, TβR2, and TβR3) have been identified, and play essential roles in mechanisms leading to palatal fusion. However, the balance between Smad-dependent/-independent signaling during palatal fusion wi...