Emodin Ameliorates Acute Pancreatitis-Associated Lung Injury Through Inhibiting the Alveolar Macrophages Pyroptosis

• Main Authors: Xiajia Wu (Author), Jiaqi Yao (Author), Qian Hu (Author), Hongxin Kang (Author), Yifan Miao (Author), Lv Zhu (Author), Cong Li (Author), Xianlin Zhao (Author), Juan Li (Author), Meihua Wan (Author), Wenfu Tang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: To investigate the protective effect of emodin in acute pancreatitis (AP)-associated lung injury and the underlying mechanisms.Methods: NaT-AP model in rats was constructed using 3.5% sodium taurocholate, and CER+LPS-AP model in mice was constructed using caerulein combined with Lipopolys...