2-phenylacetamide Separated from the seed of Lepidium apetalum Willd. inhibited renal fibrosis via MAPK pathway mediated RAAS and oxidative stress in SHR Rats

• Autors principals: Pei-pei Yuan (Autor), Meng Li (Autor), Qi Zhang (Autor), Meng-nan Zeng (Autor), Ying-ying Ke (Autor), Ya-xin Wei (Autor), Yang Fu (Autor), Xiao-ke Zheng (Autor), Wei-sheng Feng (Autor)
• Format: Llibre
• Publicat: BMC, 2023-06-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Abstract Background Renal fibrosis with Renin-angiotensin-aldosterone system (RAAS) activation and oxidative stress are one of the major complications in hypertension. 2-phenylacetamide (PA), a major active component of Lepidium apetalum Willd. (L.A), has numerous pharmacological effects. Its analog...