Corynoxine B targets at HMGB1/2 to enhance autophagy for α-synuclein clearance in fly and rodent models of Parkinson's disease

• Asıl Yazarlar: Qi Zhu (Yazar), Juxian Song (Yazar), Jia-Yue Chen (Yazar), Zhenwei Yuan (Yazar), Liangfeng Liu (Yazar), Li-Ming Xie (Yazar), Qiwen Liao (Yazar), Richard D. Ye (Yazar), Xiu Chen (Yazar), Yepiao Yan (Yazar), Jieqiong Tan (Yazar), Chris Soon Heng Tan (Yazar), Min Li (Yazar), Jia-Hong Lu (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2023-06-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Parkinson's disease (PD) is the most common neurodegenerative movement disease. It is featured by abnormal alpha-synuclein (α-syn) aggregation in dopaminergic neurons in the substantia nigra. Macroautophagy (autophagy) is an evolutionarily conserved cellular process for degradation of cellular...