Gene therapy using genome‐edited iPS cells for targeting malignant glioma

• Main Authors: Ryota Tamura (Author), Hiroyuki Miyoshi (Author), Kent Imaizumi (Author), Masahiro Yo (Author), Yoshitaka Kase (Author), Tsukika Sato (Author), Mizuto Sato (Author), Yukina Morimoto (Author), Oltea Sampetrean (Author), Jun Kohyama (Author), Munehisa Shinozaki (Author), Atsushi Miyawaki (Author), Kazunari Yoshida (Author), Hideyuki Saya (Author), Hideyuki Okano (Author), Masahiro Toda (Author)
• Format: Book
• Published: Wiley, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Glioblastoma is characterized by diffuse infiltration into the normal brain. Invasive glioma stem cells (GSCs) are an underlying cause of treatment failure. Despite the use of multimodal therapies, the prognosis remains dismal. New therapeutic approach targeting invasive GSCs is required. H...