A novel circRNA, circRACGAP1, hampers the progression of systemic lupus erythematosus via miR-22-3p-mediated AKT signalling

• المؤلفون الرئيسيون: Han-Ying Mei (مؤلف), Ju Liu (مؤلف), Xiao-Ping Shen (مؤلف), Rui Wu (مؤلف)
• التنسيق: كتاب
• منشور في: Taylor & Francis Group, 2022-08-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Background Systemic lupus erythematosus (SLE) is defined as a multisystem autoimmune disease involving various organs, of which exact molecular mechanisms remain elusive. Here, we aimed to investigate a novel circular RNA (circRNA), circRACGAP1, abnormally expressed in SLE and explored its underlyin...