Systemic Administration of a Brain Permeable Cdk5 Inhibitor Alters Neurobehavior

• मुख्य लेखकों: Alan Umfress (लेखक), Sarbjit Singh (लेखक), Kevin J. Ryan (लेखक), Ayanabha Chakraborti (लेखक), Florian Plattner (लेखक), Yogesh Sonawane (लेखक), Jayapal Reddy Mallareddy (लेखक), Edward P. Acosta (लेखक), Amarnath Natarajan (लेखक), James A. Bibb (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2022-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Cyclin-dependent kinase 5 (Cdk5) is a crucial regulator of neuronal signal transduction. Cdk5 activity is implicated in various neuropsychiatric and neurodegenerative conditions such as stress, anxiety, depression, addiction, Alzheimer's disease, and Parkinson's disease. While constitutive...