Liposomal Delivery of MIW815 (ADU-S100) for Potentiated STING Activation

• Κύριοι συγγραφείς: Nan Ji (Συγγραφέας), Minjia Wang (Συγγραφέας), Chalet Tan (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: MDPI AG, 2023-02-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Stimulator of interferon genes (STING) agonists can improve the anticancer efficacy of immune checkpoint blockade by amplifying tumor immunogenicity. However, the clinical translation of cyclic dinucleotides (CDNs) as STING agonists is hindered by their poor drug-like properties. In this study, we i...