Filociclovir Is an Active Antiviral Agent against Ocular Adenovirus Isolates In Vitro and in the Ad5/NZW Rabbit Ocular Model

Filociclovir Is an Active Antiviral Agent against Ocular Adenovirus Isolates In Vitro and in the Ad5/NZW Rabbit Ocular Model

Presently, there is no FDA- or EMA-approved antiviral for the treatment of human adenovirus (HAdV) ocular infections. This study determined the antiviral activity of filociclovir (FCV) against ocular HAdV isolates in vitro and in the Ad5/NZW rabbit ocular model. The 50% effective concentrations (EC&...

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Main Authors: Eric G. Romanowski (Author), Islam T. M. Hussein (Author), Steven C. Cardinale (Author), Michelle M. Butler (Author), Lucas R. Morin (Author), Terry L. Bowlin (Author), Kathleen A. Yates (Author), Robert M. Q. Shanks (Author), Regis P. Kowalski (Author)
Format: Book
Published: MDPI AG, 2021-03-01T00:00:00Z.
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3rd Floor Main Library

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