Systemic Design and Evaluation of Ticagrelor-Loaded Nanostructured Lipid Carriers for Enhancing Bioavailability and Antiplatelet Activity

• Главные авторы: Gi-Ho Son (Автор), Young-Guk Na (Автор), Hyun Wook Huh (Автор), Miao Wang (Автор), Min-Ki Kim (Автор), Min-Gu Han (Автор), Jin-Ju Byeon (Автор), Hong-Ki Lee (Автор), Cheong-Weon Cho (Автор)
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• Опубликовано: MDPI AG, 2019-05-01T00:00:00Z.
• Предметы: article
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Ticagrelor (TGL), a P2Y₁₂ receptor antagonist, is classified as biopharmaceutics classification system (BCS) class IV drug due to its poor solubility and permeability, resulting in low oral bioavailability. Nanostructured lipid carriers (NLC) are an efficient delivery system f...