Evaluation of p53 protein expression in Barrett esophagus

• Main Authors: Mahathi Krothapalli (Author), Jyoti Ramnath Kini (Author), Hema Kini (Author), Kausalya Kumari Sahu (Author), Suresh Shenoy (Author), Sandeep Gopal Krishna (Author), B V Tantry (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Loss of heterozygosity of p53 along with aneuploidy is deemed to be the early molecular steps in Barrett metaplasia-dysplasia-adenocarcinoma sequence. Objective biomarkers need to be used along with microscopy for risk stratification to predict the progression of Barrett esophagus (BE) t...