Trilobatin Protects Against Aβ25-35-Induced Hippocampal HT22 Cells Apoptosis Through Mediating ROS/p38/Caspase 3-Dependent Pathway

• Autori principali: Nana Chen (Autore), Jiao Wang (Autore), Yuqi He (Autore), Yingshu Xu (Autore), Yuchuan Zhang (Autore), Qihai Gong (Autore), Changyin Yu (Autore), Jianmei Gao (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2020-05-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Emerging evidence reveals that an aberrant accumulation of β-amyloid (Aβ) is the main reason of Alzheimer's disease (AD) pathogenesis. Thus, inhibition of Aβ-induced neurotoxicity may be promising therapeutic tactics to mitigate AD onset and advance. The development of agent candidates by cultu...