Signos de Leser-trélat en un carcinoma de células en anillo de sello

80 year-old man presenting with weight loss, right hypochondrium pain and vomiting, with 1 year of symptoms evolution, was admitted. Physical exam showed multiple hyperkeratotic lesions, distribuing on trunk and dorsal region, a paraneoplasic sign knowing as Leser-Trélat sign. Multiple nodular hepa...

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Bibliographic Details
Main Authors: Catarina Teles Neto (Author), Marta Valentim (Author)
Format: Book
Published: Sociedade Galega de Medicina Interna, 2022-01-01T00:00:00Z.
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100 1 0 |a Catarina Teles Neto  |e author 
700 1 0 |a Marta Valentim  |e author 
245 0 0 |a Signos de Leser-trélat en un carcinoma de células en anillo de sello 
260 |b Sociedade Galega de Medicina Interna,   |c 2022-01-01T00:00:00Z. 
500 |a 0304-4866 
500 |a 1989-3922 
500 |a 10.22546/64/2462 
520 |a 80 year-old man presenting with weight loss, right hypochondrium pain and vomiting, with 1 year of symptoms evolution, was admitted. Physical exam showed multiple hyperkeratotic lesions, distribuing on trunk and dorsal region, a paraneoplasic sign knowing as Leser-Trélat sign. Multiple nodular hepatic hypoechogenic formations were detected on the echography. Analytically: CEA 2627 ng/mL. CT body scan: lymphatic, pulmonary, suprarenal and hepatic metastasis, without evidence of the primary tumor. Upper Endoscopy and Colonoscopy were performed, without alterations. The Hepatic biopsy revealed: infiltration by well differentiated carcinoma, with mucus lakes and numerous signet-ring cells, whose immunohistochemical profile was compatible with origin in the gastrointestinal tract. 
546 |a EN 
546 |a ES 
546 |a GL 
546 |a PT 
690 |a sinal de leser-trélat 
690 |a células en anillo de sello 
690 |a Medicine 
690 |a R 
690 |a Internal medicine 
690 |a RC31-1245 
655 7 |a article  |2 local 
786 0 |n Galicia Clínica, Vol 83, Iss 1, Pp 53-53 (2022) 
787 0 |n https://galiciaclinica.info/publicacion.asp?f=2462 
787 0 |n https://doaj.org/toc/0304-4866 
787 0 |n https://doaj.org/toc/1989-3922 
856 4 1 |u https://doaj.org/article/f4b45c4715764eb2be31f546b89a9832  |z Connect to this object online.