Glycosaminoglycans as Multifunctional Anti-Elastase and Anti-Inflammatory Drugs in Cystic Fibrosis Lung Disease

Neutrophil elastase (NE) is a major protease in the airways of patients with cystic fibrosis (CF) that activates airway inflammation by several mechanisms. NE stimulates epithelial toll like receptors (TLR) resulting in cytokine upregulation and release, upregulates MUC5AC, a major airway mucin, deg...

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Main Authors: Judith A. Voynow (Author), Shuo Zheng (Author), Apparao B. Kummarapurugu (Author)
Format: Book
Published: Frontiers Media S.A., 2020-07-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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