Development and validation of a 6-plex Luminex-based assay for measuring human serum antibodies to group B streptococcus capsular polysaccharides

• Main Authors: Michelle A. Gaylord (Author), Melissa Larrier (Author), Donna Giordano-Schmidt (Author), Christopher D. Grube (Author), Suddham Singh (Author), Ha H. Nguyen (Author), Andrew McKeen (Author), Charles Y. Tan (Author), Annaliesa S. Anderson (Author), Warren V. Kalina (Author), Danka Pavliakova (Author), Peter C. Giardina (Author)
• Format: Book
• Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACTSix serotypes (Ia, Ib, II, III, IV, and V) cause nearly all group B streptococcal (GBS) disease globally. Capsular polysaccharide (CPS) conjugate vaccines aim to prevent GBS disease, however, licensure of a vaccine would depend on a standardized serological assay for measuring anti-CPS IgG r...