Use of recombinant microRNAs as antimetabolites to inhibit human non-small cell lung cancer

• Main Authors: Yixin Chen (Author), Mei-Juan Tu (Author), Fangwei Han (Author), Zhenzhen Liu (Author), Neelu Batra (Author), Primo N. Lara (Author), Hong-Wu Chen (Author), Huichang Bi (Author), Ai-Ming Yu (Author)
• Format: Book
• Published: Elsevier, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

During the development of therapeutic microRNAs (miRNAs or miRs), it is essential to define their pharmacological actions. Rather, miRNA research and therapy mainly use miRNA mimics synthesized in vitro. After experimental screening of unique recombinant miRNAs produced in vivo, three lead antiproli...