SH003 overcomes drug resistance and immune checkpoints by inhibiting JAK-STAT3 signaling in MCF7/ADR cells

• Main Authors: Jin Mo Ku (Author), Se Hyang Hong (Author), Hyo In Kim (Author), Min Jeong Kim (Author), Su-Jeong Ku (Author), Kwang-Rok Bae (Author), Hye Sook Seo (Author), Yong Cheol Shin (Author), Seong-Gyu Ko (Author)
• 格式: 图书
• 出版: Elsevier, 2021-11-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Background: Breast cancer has the most commonly diagnosed malignancy cancer worldwide in women and has a high mortality. Various anticancer drugs to treat breast cancer have been developed and tested but have failed because of drug resistance. Objectives: The efficacy of SH003 against doxorubicin-re...