Inhibition of Cathepsin S Produces Neuroprotective Effects after Traumatic Brain Injury in Mice

• Main Authors: Jianguo Xu (Author), Handong Wang (Author), Ke Ding (Author), Xinyu Lu (Author), Tao Li (Author), Jiawei Wang (Author), Chunxi Wang (Author), Jian Wang (Author)
• Format: Book
• Published: Hindawi Limited, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cathepsin S (CatS) is a cysteine protease normally present in lysosomes. It has long been regarded as an enzyme that is primarily involved in general protein degradation. More recently, mounting evidence has shown that it is involved in Alzheimer disease, seizures, age-related inflammatory processes...