New Membrane Active Antibacterial and Antiviral Amphiphiles Derived from Heterocyclic Backbone of Pyridinium-4-Aldoxime

• Main Authors: Doris Crnčević (Author), Lucija Krce (Author), Mislav Cvitković (Author), Zlatko Brkljača (Author), Antonio Sabljić (Author), Elma Vuko (Author), Ines Primožič (Author), Renata Odžak (Author), Matilda Šprung (Author)
• Format: Book
• Published: MDPI AG, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Quaternary ammonium salts (QAS) are irreplaceable membrane-active antimicrobial agents that have been widely used for nearly a century. Cetylpyridinium chloride (CPC) is one of the most potent QAS. However, recent data from the literature indicate that CPC activity against resistant bacterial strain...