Stimulating intestinal GIP release reduces food intake and body weight in mice

• Main Authors: Jo E. Lewis (Author), Danae Nuzzaci (Author), Paula-Peace (Author), Mireia Montaner (Author), Elisabeth O'Flaherty (Author), Tamana Darwish (Author), Marito Hayashi (Author), Stephen D. Liberles (Author), David Hornigold (Author), Jacqueline Naylor (Author), David Baker (Author), Fiona M. Gribble (Author), Frank Reimann (Author)
• Format: Book
• Published: Elsevier, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Glucose dependent insulinotropic polypeptide (GIP) is well established as an incretin hormone, boosting glucose-dependent insulin secretion. However, whilst anorectic actions of its sister-incretin glucagon-like peptide-1 (GLP-1) are well established, a physiological role for GIP in appet...