Cover Image

Stimulating intestinal GIP release reduces food intake and body weight in mice

Objective: Glucose dependent insulinotropic polypeptide (GIP) is well established as an incretin hormone, boosting glucose-dependent insulin secretion. However, whilst anorectic actions of its sister-incretin glucagon-like peptide-1 (GLP-1) are well established, a physiological role for GIP in appet...

Full description

Saved in:

Bibliographic Details
Main Authors:	Jo E. Lewis (Author), Danae Nuzzaci (Author), Paula-Peace (Author), Mireia Montaner (Author), Elisabeth O'Flaherty (Author), Tamana Darwish (Author), Marito Hayashi (Author), Stephen D. Liberles (Author), David Hornigold (Author), Jacqueline Naylor (Author), David Baker (Author), Fiona M. Gribble (Author), Frank Reimann (Author)
Format:	Book
Published:	Elsevier, 2024-06-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Relaxin/insulin-like family peptide receptor 4 (Rxfp4) expressing hypothalamic neurons modulate food intake and preference in mice
by: Jo E. Lewis, et al.
Published: (2022)

Nutrient sensing in the nucleus of the solitary tract mediates non-aversive suppression of feeding via inhibition of AgRP neurons
by: Anthony H. Tsang, et al.
Published: (2020)

Loss of GIPR in LEPR cells impairs glucose control by GIP and GIP:GLP-1 co-agonism without affecting body weight and food intake in mice
by: Seun Akindehin, et al.
Published: (2024)

Tirzepatide, GIP(1-42) and GIP(1-30) display unique signaling profiles at two common GIP receptor variants, E354 and Q354
by: Tayla A. Rees, et al.
Published: (2024)

Kondisi Kemasan dan Pemasaran Bahan Stone Gips (Gips Tipe III) di Jakarta (Juli 1996-1998)
by: Mia Damiyanti
Published: (2015)

Rapid sensing of l-leucine by human and murine hypothalamic neurons: Neurochemical and mechanistic insights
by: Nicholas Heeley, et al.
Published: (2018)

The effect of gastrointestinal pathogen panel (GIP) on antibiotic management
by: Christopher F. Saling, et al.
Published: (2021)

Population pharmacokinetics of the GIP/GLP receptor agonist tirzepatide
by: Karen Schneck, et al.
Published: (2024)

Physiological roles of the GIP receptor in murine brown adipose tissue
by: Jacqueline L. Beaudry, et al.
Published: (2019)

GIP receptor agonism blocks chemotherapy-induced nausea and vomiting
by: Tito Borner, et al.
Published: (2023)

The Effect of Cell Surface Expression and Linker Sequence on the Recruitment of Arrestin to the GIP Receptor
by: Suleiman Al-Sabah, et al.
Published: (2020)

Peroxiredoxin 6: The Protector of Male Fertility
by: Cristian O'Flaherty
Published: (2018)

Reactive Oxygen Species and Male Fertility
by: Cristian O'Flaherty
Published: (2020)

MENINGKATKAN KREATIVITAS ANAK USIA DINI MELALUI KEGIATAN SENI PATUNG DARI BAHAN GIPS
by: WARDHANI, ANISA SUCIATI
Published: (2015)

Monomeric GLP-1/GIP/glucagon triagonism corrects obesity, hepatosteatosis, and dyslipidemia in female mice
by: Sigrid Jall, et al.
Published: (2017)

Optimized GIP analogs promote body weight lowering in mice through GIPR agonism not antagonism
by: Piotr A. Mroz, et al.
Published: (2019)

Unity and Language A Study in the Philosophy of Johann Georg Hamann
by: O'Flaherty, James C.
Published: (1952)

Unity and Language A Study in the Philosophy of Johann Georg Hamann
by: O'Flaherty, James C.
Published: (1952)

Anorectic and aversive effects of GLP-1 receptor agonism are mediated by brainstem cholecystokinin neurons, and modulated by GIP receptor activation
by: Alessia Costa, et al.
Published: (2022)

INITIATING PATIENTS ON GLP-1/COMBINED GLP-1 AND GIP AGONISTS: A QUALITY IMPROVEMENT PROJECT
by: Shreya Srivastava, MD, MPH
Published: (2024)

Next generation GLP-1/GIP/glucagon triple agonists normalize body weight in obese mice
by: Patrick J. Knerr, et al.
Published: (2022)

Citrate Promotes Nitric Oxide Production during Human Sperm Capacitation
by: Diego Loggia, et al.
Published: (2024)

Keeping Public Health Clean: Food Policy Barriers and Opportunities in the Era of the Industrial Epidemics
by: Martin O'Flaherty, et al.
Published: (2016)

Healthcare professionals' perceptions and management of obesity & knowledge of glucagon, GLP‐1, GIP receptor agonists, and dual agonists
by: W. Timothy Garvey, et al.
Published: (2024)

Tirzepatide - a novel dual GLP-1 and GIP receptor agonist used in pharmacotherapy of obesity: A literature review
by: Bartłomiej Stachyra, et al.
Published: (2023)

TGR5, GLP-1, and GIP expression in diabetic Wistar rats in response to Ficus exasperata vahl leaf extract
by: Olorunsola Israel Adeyomoye, et al.
Published: (2024)

Spatiotemporal GLP-1 and GIP receptor signaling and trafficking/recycling dynamics induced by selected receptor mono- and dual-agonists
by: Aaron Novikoff, et al.
Published: (2021)

The incretin hormone GIP is upregulated in patients with atherosclerosis and stabilizes plaques in ApoE−/− mice by blocking monocyte/macrophage activation
by: Florian Kahles, et al.
Published: (2018)

Establishing a Relationship between In Vitro Potency in Cell-Based Assays and Clinical Efficacious Concentrations for Approved GLP-1 Receptor Agonists
by: Alessandro Boianelli, et al.
Published: (2024)

A Physiologically‐Based Quantitative Systems Pharmacology Model of the Incretin Hormones GLP‐1 and GIP and the DPP4 Inhibitor Sitagliptin
by: Pavel Balazki, et al.
Published: (2020)

Attenuated secretion of glucose-dependent insulinotropic polypeptide (GIP) does not alleviate hyperphagic obesity and insulin resistance in ob/ob mice
by: Satoko Shimazu-Kuwahara, et al.
Published: (2017)

Peroxiredoxin 6 Peroxidase and Ca<sup>2+</sup>-Independent Phospholipase A<sub>2</sub> Activities Are Essential to Support Male-Mouse Fertility
by: Edrian Bumanlag, et al.
Published: (2022)

The scars of the past? Childhood health and health differentials in later life
by: Jack Lam, et al.
Published: (2019)

LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of concept
by: Tamer Coskun, et al.
Published: (2018)

Designing a Dual GLP-1R/GIPR Agonist from Tirzepatide: Comparing Residues Between Tirzepatide, GLP-1, and GIP
by: Wang L
Published: (2022)

Protective Effect of GIP against Monosodium Glutamate-Induced Ferroptosis in Mouse Hippocampal HT-22 Cells through the MAPK Signaling Pathway
by: Jiwon Ko, et al.
Published: (2022)

A case-control analysis of common variants in GIP with type 2 diabetes and related biochemical parameters in a South Indian population
by: Kumar Harish, et al.
Published: (2010)

Limited impact on glucose homeostasis of leptin receptor deletion from insulin- or proglucagon-expressing cells
by: Helen Soedling, et al.
Published: (2015)

Serotonergic modulation of the activity of GLP-1 producing neurons in the nucleus of the solitary tract in mouse
by: Marie K. Holt, et al.
Published: (2017)

A Novel Combination of γ-Tocopherol-Rich Mixture of Tocopherols and Ascorbic Acid Restores Fertility in Cases of Tyrosine Nitration-Associated Male Infertility in Mice
by: Eleonora Scarlata, et al.
Published: (2020)