Sleep Deprivation Triggers Mitochondrial DNA Release in Microglia to Induce Neural Inflammation: Preventative Effect of Hydroxytyrosol Butyrate

• Main Authors: Yachong Hu (Author), Yongyao Wang (Author), Yifang Wang (Author), Yuxia Zhang (Author), Zhen Wang (Author), Xiaohong Xu (Author), Tinghua Zhang (Author), Tiantian Zhang (Author), Shuangxi Zhang (Author), Ranrui Hu (Author), Le Shi (Author), Xudong Wang (Author), Jin Li (Author), Hui Shen (Author), Jiankang Liu (Author), Mami Noda (Author), Yunhua Peng (Author), Jiangang Long (Author)
• Format: Book
• Published: MDPI AG, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Sleep deprivation (SD) triggers mitochondrial dysfunction and neural inflammation, leading to cognitive impairment and mental issues. However, the mechanism involving mitochondrial dysfunction and neural inflammation still remains unclear. Here, we report that SD rats exhibited multiple behavioral d...