Apremilast Improves Endothelial Glycocalyx Integrity, Vascular and Left Ventricular Myocardial Function in Psoriasis

• Main Authors: Ignatios Ikonomidis (Author), George Pavlidis (Author), Nikolaos Kadoglou (Author), George Makavos (Author), Konstantinos Katogiannis (Author), Aikaterini Kountouri (Author), John Thymis (Author), Gavriella Kostelli (Author), Irini Kapniari (Author), Konstantinos Theodoropoulos (Author), John Parissis (Author), Pelagia Katsimbri (Author), Evangelia Papadavid (Author), Vaia Lambadiari (Author)
• Format: Book
• Published: MDPI AG, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The phosphodiesterase 4 inhibitor apremilast is used for the treatment of psoriasis. We investigated the effects of apremilast on endothelial glycocalyx, vascular and left ventricular (LV) myocardial function in psoriasis. One hundred and fifty psoriatic patients were randomized to apremilast (<i...