Over-expression of Tgs1 in Mycobacterium marinum enhances virulence in adult zebrafish

• Main Authors: Ding-qian Liu (Author), Jun-li Zhang (Author), Zhi-fen Pan (Author), Jun-tao Mai (Author), Heng-jun Mei (Author), Yue Dai (Author), Lu Zhang (Author), Qing-zhong Wang (Author)
• Format: Book
• Published: Elsevier, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), can persist in the host for decades without causing TB symptoms and can cause a latent infection, which is an intricate challenge of current TB control. The DosR regulon, which contains approximately 50 genes, is crucial in...