Preparation and Characterization of Silk Fibroin Nanoparticles as a Potential Drug Delivery System for 5-Fluorouracil

• Main Authors: Hamid Rahmani (Author), Ali Fattahi (Author), Komail Sadrjavadi (Author), Salar Khaledian (Author), Yalda Shokoohinia (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2019-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: The aim of this study is to prepare 5-fluorouracil (5-FU) loaded silk fibroin nanoparticles (SFNPs) and to achieve a controlled release delivery system with the high loading capacity. Methods: SFNPs with 1:1, 1:3, and 1:10 ratios of 5-FU to silk fibroin were prepared. SFNPs were characteriz...