Integrative bioinformatics analysis characterizing the role of EDC3 in mRNA decay and its association to intellectual disability

• Main Authors: Ute Scheller (Author), Kathrin Pfisterer (Author), Steffen Uebe (Author), Arif B. Ekici (Author), André Reis (Author), Rami Jamra (Author), Fulvia Ferrazzi (Author)
• Format: Book
• Published: BMC, 2018-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Decapping of mRNA is an important step in the regulation of mRNA turnover and therefore of gene expression, which is a key process controlling development and homeostasis of all organisms. It has been shown that EDC3 plays a role in mRNA decapping, however its function is not wel...