Pharmacokinetics, metabolite profiling, safety, and tolerability of inhalation aerosol of 101BHG-D01, a novel, long-acting and selective muscarinic receptor antagonist, in healthy Chinese subjects

• Main Authors: Huaye Gao (Author), Jintong Li (Author), Xiaoping Chen (Author), Zhanguo Sun (Author), Gang Cui (Author), Minlu Cheng (Author), Li Ding (Author)
• 格式: 圖書
• 出版: Frontiers Media S.A., 2022-12-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

101BHG-D01 is a novel, long-acting, selective muscarinic receptor antagonist for the treatment of chronic obstructive pulmonary disease (COPD). A single-site, randomized, double-blind, placebo-controlled and dose-escalation study of 101BHG-D01 inhalation aerosol was conducted to evaluate its pharmac...