Feasibility of the estimation of octanol-water distribution coefficients of acidic drugs by microemulsion electrokinetic chromatography

• Main Authors: Alejandro Fernández-Pumarega1 (Author), Susana Amézqueta1 (Author), Elisabet Fuguet (Author), Martí Rosés (Author)
• 格式: 图书
• 出版: International Association of Physical Chemists (IAPC), 2018-03-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Previous studies have shown that a microemulsion electrokinetic chromatography (MEEKC) system can estimate the logarithm of the octanol-water partition coefficient (log Po/w) of neutral solutes. In the present work, the applicability of the method to partially and fully ionized acids has been evalua...