Feasibility of the estimation of octanol-water distribution coefficients of acidic drugs by microemulsion electrokinetic chromatography

Previous studies have shown that a microemulsion electrokinetic chromatography (MEEKC) system can estimate the logarithm of the octanol-water partition coefficient (log Po/w) of neutral solutes. In the present work, the applicability of the method to partially and fully ionized acids has been evalua...

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Main Authors: Alejandro Fernández-Pumarega1 (Author), Susana Amézqueta1 (Author), Elisabet Fuguet (Author), Martí Rosés (Author)
Format: Book
Published: International Association of Physical Chemists (IAPC), 2018-03-01T00:00:00Z.
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