Preparation, Physicochemical Characterization and Anti-Fungal Evaluation of Amphotericin B-Loaded PLGA-PEG-Galactosamine Nanoparticles

• Main Authors: Ghobad Mohammadi (Author), Mostafa Fathian-Kolahkaj (Author), Pardis Mohammadi (Author), Khosro Adibkia (Author), Ali Fattahi (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: The present study aimed to formulate PLGA and PLGA-PEG-galactosamine nanoparticles (NPs) loaded with amphotericin B with appropriate physicochemical properties and antifungal activity. PLGA was functionalized with GalN to increase the adhesion and antifungal activity of NPs against Candida...